Multiple Sclerosis

Multiple sclerosis (MS) involves an immune-mediated process in which an abnormal response of the body’s immune system is directed against the central nervous system (CNS).  The CNS is made up of the brain, spinal cord and optic nerves.

Within the CNS, the immune system causes inflammation that damages myelin — the fatty substance that surrounds and insulates the nerve fibers — as well as the nerve fibers themselves, and the specialized cells that make myelin.

  • When myelin or nerve fibers are damaged or destroyed in MS, messages within the CNS are altered or stopped completely.
  • Damage to areas of the CNS may produce a variety of neurological symptoms that will vary among people with MS in type and severity
  • The damaged areas develop scar tissue which gives the disease its name – multiple areas of scarring or multiple sclerosis.
  • The cause of MS is not known, but it is believed to involve genetic susceptibility, abnormalities in the immune system and environmental factors that combine to trigger the disease.
  • People with MS typically experience one of four disease courses. There are over a dozen treatments to help modify the MS disease process.

Managing MS is an ongoing process, beginning with the very first symptoms and continuing throughout the disease course. It’s never too soon or too late to think about how to access high quality, comprehensive, interdisciplinary care. We are here to help answer questions, guide you through the diagnosis process, and offer treatment solutions that enhance your wellness and quality of life.


National Multiple Sclerosis Society

Ajay Gupta, M.D.

Ajay Gupta, M.D.


Dr. Gupta received his medical training at MP Shah Medical College in Jamnagar, India. His residency in neurology was accomplished at the Medical College of Ohio, Toledo, Ohio. Dr. Gupta furthered his professional training after his residency by completing dual fellowships in electroencephalography/ epilepsy and in multiple sclerosis/ neuro immunology at the Medical College of Ohio and at the National Institute of Health in Bethesda, Maryland.

- M.B.B.S., 1978, MP Shah Medical College, Jamnagar, India

- Chief Resident in Neurology, Medical College of Ohio, Toledo, Ohio, 1984-1985
- Resident in Neurology, Medical College of Ohio, Toledo, Ohio, 1982-1985
- Resident in Generat Medicine, MP Shah Medical College and Irwin Group of Hospitals, Jamnagar, India, 1980-1981

- Board Certified, Neurology
- Board eligible in Electroencephalography

- American Academy of Neurology
- Indiana State Medical Association
- Indiana Neurological Society
- Fort Wayne Medical Society